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Search Results for " poly (adp-ribose) polymerase 1 "
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Targets Recommended: PARP

22

抑制剂 & 化合物

6

天然产物

1735

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T16807 Rucaparib monocamsylate

瑞卡帕布樟脑磺酸盐,Rucaparib Camsylate

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Rucaparib monocamsylate (Rucaparib Camsylate) 是一种口服有效的 PARP 蛋白抑制剂,对 PARP-1 的Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂,有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T6329 3-Aminobenzamide

3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
3-Aminobenzamide (PARP-IN-1) 是一种有效的 PARP 抑制剂,在 CHO 细胞中,对 PARP 的 IC50值约为 50 nM。它是再灌注过程中氧化剂诱导的肌细胞功能障碍的介质。
T9891 PARP1-IN-8 

N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) 是PARP1的有效抑制剂(IC50 = 97 nM)。
T6253 Talazoparib

LT-673,BMN-673,他拉唑帕利

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Talazoparib (LT-673) 是一种具有口服活性的 PARP 1/2抑制剂,IC50为0.58 nM,具有抗肿瘤活性。它抑制 PARP1 和 PARP2 酶活性的 Ki 值分别为 1.2 nM 和 0.87 nM。
T4463 Rucaparib

AG-14447,PF-01367338,瑞卡帕布,AG014699

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Rucaparib (PF-01367338) 是一种口服有效的 PARP 蛋白抑制剂,对 PARP-1 的 Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂,有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T6127 Rucaparib Phosphate

AG-014699 phosphate,PF-01367338,芦卡帕利,AG-014699,瑞卡帕布磷酸盐,PF-01367338 phosphate

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Rucaparib Phosphate (PF-01367338 phosphate) 是一种口服有效的PARP 蛋白抑制剂,对 PARP-1 的Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂,有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。
T8619 8-CHLOROQUINAZOLIN-4(1H)-ONE

Others Others
8-CHLOROQUINAZOLIN-4(1H)-ONE 是 Poly [ADP-ribose] 聚合酶 1(人)的抑制剂。
T12365 PARP/PI3K-IN-1

PARP; PI3K Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
PARP/PI3K-IN-1 是一种 新型双重聚(ADP-核糖)聚合酶(PARP)和磷酸肌醇 3-激酶(PI3K)双重抑制剂,具有抗癌、抗肿瘤和抗癌细胞增殖活性,可用于研究乳腺癌、胰腺癌和肺癌。
T72553 ARTD10/PARP10-IN-1

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
ARTD10/PARP10-IN-1 是一种强效性的 PARP 抑制剂,抑制单 ADP 核糖转移酶 ARTD7/PARP15,ARTD8/PARP14,ARTD10/PARP10 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1),具有潜在的抗癌抗肿瘤活性,可用于研究前列腺癌和乳腺癌。
T22749 DR2313

DR 2313

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
DR2313 是一种选择性,竞争性的和可透过血脑屏障的PARP 抑制剂,对PARP-1和PARP-2的IC50值分别为 0.20 和 0.24 μM。它在体内外均有对缺血性损伤的神经保护作用。
T3157 COH29

RNR Inhibitor COH29

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
COH29 (RNR Inhibitor COH29) 是一种口服可用的芳香族取代噻唑,是人类核糖核苷酸还原酶 (RNR) 的抑制剂,具有潜在的抗肿瘤活性。它抑制核糖核苷酸还原酶的IC50为 16 μM。
T78401 pNP-ADPr disodium

ADP-ribose-pNP disodium

pNP-ADPr 二钠是一种用于检测Poly(ADP-ribose) glycohydrolase (PARG)和ADP-ribosyl hydrolase 3 (ARH3)活性的比色底物。它也适用于poly(ADP-ribose)polymerase (PARP)酶相关研究。
T13333 WD2000-012547

Others Others
WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).
T61879 PARP1-IN-7

PARP1-IN-7 是一种聚 ADP 核糖聚合酶-1(PARP1)的抑制剂,作为抗癌剂。
T81249 Ru3

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Ru3是一种poly(ADP-ribose)polymerase 1抑制剂,能够通过诱导DNA损伤、抑制DNA修复机制、扰乱细胞周期、降低线粒体膜电位及增加reactive oxygen species水平来诱导MCF-7细胞的apoptosis。
T72554 ARTD10/PARP10-IN-2

ARTD10/PARP10-IN-2 是一种强效、非选择性的PARP 抑制剂。ARTD10/PARP10-IN-2 靶向单 ADP 核糖转移酶 (ARTD10/PARP10) 和聚 ADP-核糖聚合酶-1 (ARTD1/PARP1),IC50分别为 2.0 μM,和 9.7 μM。
T36702 CAY10753

CAY10753 is an inhibitor of tankyrase 2 (TNKS2; IC50= 0.3 nM).1It is selective for TNKS2 over TNKS1 (IC50= 6.1 nM), as well as poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 89.6 and 37.8 nM, respectively). CAY10753 inhibits proliferation of DLD-1 colorectal cancer cells when used at a concentration of 1 μM. 1.Tomassi, S., Pfahler, J., Mautone, N., et al.From PARP1 to TNKS2 inhibition: A structure-based approachMed. Chem. Lett.(2020)
T36703 CAY10760

CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing BxPC-3 pancreatic cancer cells when used at a concentration of 20 μM. CAY10760 (20 μM) decreases proliferation of BxPC-3, as well as mutantBRCA2-expressing Capan-1, cancer cells when used alone or in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib . 1.Bag...
T79608 DPP

JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
DPP,一种含紫檀芪衍生轴向配体的铂(IV)络合物,能够抑制乳腺癌(BC)细胞的JAK2-STAT3通路并显示出抗增殖特性。它通过激活caspase-3和裂解聚ADP-核糖聚合酶诱导细胞凋亡(apoptosis),同时促进树突状细胞成熟及抗原呈现功能,并已证明体内具有安全性。
T72017 6(5H)-Phenanthridinone

6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes. In vivo, 6(5H)-phenanthridinone reduces spinal cord expression of inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of experimenta...
T75074 6-Methoxypurine-9-β-D-5’(R)-C-methylriboside

6-Methoxypurine-9-β-D-5’(R)-C-methylriboside 是一种嘌呤碱基,属于次黄嘌呤似物,主要在肌肉组织中发现。作为黄嘌呤在嘌呤氧化酶作用下的代谢产物,次黄嘌呤具备显著的抗炎性质,并可作为内源性 poly(ADP-ribose) polymerase (PARP) 的抑制剂。其通过抑制 PARP 活性,防止过氧亚硝酸盐引起的线粒体去极化及次级超氧化物的产生,展现出细胞保护作用。同时,次黄嘌呤也被用作缺氧的生物标志物。
T83854 BRC4wt TFA

BRC4wt是一种从人类BRCA2的BRC4重复区(1521-1536)衍生而来的乙酰化肽,并且是BRCA2与RAD51之间的蛋白质-蛋白质相互作用的抑制剂。当与阳离子穿膜肽(Arg)9结合时,BRC4wt缩短了体外DNA复制轨迹长度,并降低了由DNA拓扑异构酶I抑制剂坎普特西汀引起的DNA损伤的同源修复频率,同时也增强了聚(ADP-核糖)聚合酶(PARP)抑制剂奥拉帕尼在HeLa人类宫颈癌细胞和U2OS人类骨肉瘤细胞中诱导的细胞死亡,但在非癌症细胞hTERT RPE-1、MRC-5或MCF-10A中则不然。

化合物

Rucaparib monocamsylate
Cat.No: T16807
Synonym: 瑞卡帕布樟脑磺酸盐,Rucaparib Camsylate
Target: PARP
3-Aminobenzamide
Cat.No: T6329
Synonym: 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001
Target: PARP
PARP1-IN-8 
Cat.No: T9891
Synonym: N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide
Target: PARP
Talazoparib
Cat.No: T6253
Synonym: LT-673,BMN-673,他拉唑帕利
Target: PARP
Rucaparib
Cat.No: T4463
Synonym: AG-14447,PF-01367338,瑞卡帕布,AG014699
Target: PARP
Rucaparib Phosphate
Cat.No: T6127
Synonym: AG-014699 phosphate,PF-01367338,芦卡帕利,AG-014699,瑞卡帕布磷酸盐,PF-01367338 phosphate
Target: PARP
8-CHLOROQUINAZOLIN-4(1H)-ONE
Cat.No: T8619
Synonym:
Target: Others
PARP/PI3K-IN-1
Cat.No: T12365
Synonym:
Target: PARP, PI3K
ARTD10/PARP10-IN-1
Cat.No: T72553
Synonym:
Target: PARP
DR2313
Cat.No: T22749
Synonym: DR 2313
Target: PARP
COH29
Cat.No: T3157
Synonym: RNR Inhibitor COH29
Target: DNA/RNA Synthesis
pNP-ADPr disodium
Cat.No: T78401
Synonym: ADP-ribose-pNP disodium
Target:
WD2000-012547
Cat.No: T13333
Synonym:
Target: Others
PARP1-IN-7
Cat.No: T61879
Synonym:
Target:
Ru3
Cat.No: T81249
Synonym:
Target: PARP
ARTD10/PARP10-IN-2
Cat.No: T72554
Synonym:
Target:
CAY10753
Cat.No: T36702
Synonym:
Target:
CAY10760
Cat.No: T36703
Synonym:
Target:
DPP
Cat.No: T79608
Synonym:
Target: JAK
6(5H)-Phenanthridinone
Cat.No: T72017
Synonym:
Target:
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside
Cat.No: T75074
Synonym:
Target:
BRC4wt TFA
Cat.No: T83854
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T8150 Nudifloramide

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺

PARP; Endogenous Metabolite Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) 是烟酰胺-腺嘌呤二核苷酸(NAD) 降解的一种最终产物,可显著抑制PARP-1活性。
T2851 Daphnetin

7,8-Dihydroxycoumarin,Daphnetol,瑞香素

EGFR; PKA; PKC; Parasite; Autophagy Angiogenesis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Daphnetin (7,8-Dihydroxycoumarin) 是从 Genus Daphne 中分离得到的香豆素衍生物,有抗氧化、抗炎、抗疟疾和解热作用,可用于凝血功能障碍、类风湿性关节炎等疾病的相关研究。
T4085 Paris saponin VII

重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Apoptosis; BCL; Others; PARP; p38 MAPK; Akt; Caspase; P-gp; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Membrane transporter/Ion channel; Neuroscience; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Paris saponin VII (Dioscini) 是从延龄草的根和根茎中分离的一种甾体皂苷。它减弱线粒体膜电位,增加凋亡相关蛋白的表达,并降低Bcl-2、caspase-9、caspase-3、PARP-1和p-Akt 的蛋白表达水平。它在 K562/ADR 细胞中诱导强烈的自噬,可研究白血病。
T40834 5-Hydroxymethyl-2'-deoxycytidine

5hmdC,2'-脱氧-5-(羟甲基)胞啶

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
5-Hydroxymethyl-2'-deoxycytidine 是 DNA 中 5-methyl-2'-deoxycytidine (5-mdC) 的氧化衍生物,引起DNA损伤反应,染色体畸变,复制叉损伤和细胞活力丧失。5-Hydroxymethyl-2’-deoxycytidine 复制叉不稳定性与染色质上聚(ADP-核糖)聚合酶1(PARP1)的存在有关。
T2860 Vanillyl Alcohol

4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol

Apoptosis; Others Apoptosis; Others
Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) 是一种酚类醇,具有抗血管生成、抗惊厥、抗炎、抗氧化、神经保护和抗伤害活性。它由香兰素衍生而来,在食品和饮料中用作调味剂。
T6S2391 L-Chicoric Acid

(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
L-Chicoric Acid (trans-Caffeoyltartaric acid) 是一种二咖啡酰酒石酸,是一种选择性可逆的 HIV-1 整合酶抑制剂,IC50约为 100 nM。它还可抑制 HIV-1 复制。

天然产物

Nudifloramide
Cat.No: T8150
Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺
Target: PARP, Endogenous Metabolite
Daphnetin
Cat.No: T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol,瑞香素
Target: EGFR, PKA, PKC, Parasite, Autophagy
Paris saponin VII
Cat.No: T4085
Synonym: 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
5-Hydroxymethyl-2'-deoxycytidine
Cat.No: T40834
Synonym: 5hmdC,2'-脱氧-5-(羟甲基)胞啶
Target: PARP
Vanillyl Alcohol
Cat.No: T2860
Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,香兰醇,Vanillin alcohol,Vanillic alcohol
Target: Apoptosis, Others
L-Chicoric Acid
Cat.No: T6S2391
Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸
Target: Others, HIV Protease
Cat. No. Product Name Species Expression System
TMPY-01188 PARP Protein, Human, Recombinant (His)

ADPRT1,ADPRT,pADPRT-...

Human Baculovirus Insect Cells
PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8.
TMPY-02465 PARP Protein, Mouse, Recombinant (His)

AI893648,Adprp,5830444G22Rik,C80510,sPARP-...

Mouse Baculovirus Insect Cells
PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 115 kDa and the accession number is Q921K2.
TMPY-02421 PARP3 Protein, Human, Recombinant (His & GST)

ARTD3,IRT1,ADPRTL2,ADPRTL3,po...

Human Baculovirus Insect Cells
Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular response to DNA double-strand breaks (DSBs), plays an essential role in the maintenance of genome integrity. The ADP ribosyl transferase [poly(ADP-ribose) polymerase] ARTD3(PARP3) is a newly characterized member of the ARTD(PARP) family that catalyzes the reaction of ADP ribosylation...
TMPY-02831 Caspase-7 Protein, Human, Recombinant (His)

ICE-LAP3,LICE2,MCH3,CASP-7,caspase 7, apoptosis-related cyst...

Human E. coli
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are two major classes of caspases: initiators and effectors. The initiator isoforms (caspases-1,-4,-5,-8,-9,-10,-11,-12) are activated by, and interact with, upstream adaptor molecules through protein-protein interaction domains known as CARD and DED. Effector caspases (-3,-6,-7) are r...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...

Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant

CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...

Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2,ACE-2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

RSPO,CRISTIN3,R-spondin 1

Human HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His)

W282,W264,CEA,CD66D,CGM1,MGC11987...

Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-01938 CD98 Protein, Human, Recombinant (His)

4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01894 SIGIRR Protein, Human, Recombinant (His)

TIR8,single immunoglobulin and toll-interleukin 1 r...

Human HEK293 Cells
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His)

ActRIIB,activin A receptor, type IIB,4930516B21...

Mouse HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01258 IL-13RA1 Protein, Human, Recombinant (His)

NR4,interleukin 13 receptor, alpha 1,CD2

Human HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His)

D1S166E,tumor necrosis factor receptor sup...

Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-00861 IL-33 Protein, Human, Recombinant

IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...

Human E. coli
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His)

FLK2,FLK-2,CD135,STK1,fms-related tyrosine...

Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His)

KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...

Human HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His)

thymic stromal lymphopoietin

Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

R-spondin 2,CRISTIN2

Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-02813 ErbB4 Protein, Human, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 4

Human,Rhesus HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01883 EPOR Protein, Human, Recombinant (His)

erythropoietin receptor,EPO-R

Human HEK293 Cells
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant

LAG-3,lymphocyte-activation gene 3,CD223

Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)

ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...

Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular c...

Human HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-04165 FGFR3 Protein, Human, Recombinant (His)

JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-01137 HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-02033 CD44 Protein, Human, Recombinant (His)

CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...

Human HEK293 Cells
CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-01744 ACVR2A Protein, Human, Recombinant (His)

activin A receptor, type IIA,ACVR2,ACTRII

Human HEK293 Cells
ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His)

BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3

Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-01851 CD73 Protein, Human, Recombinant (His)

eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...

Human HEK293 Cells
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-01949 CD19 Protein, Human, Recombinant (His)

CD19 molecule,B4,CVID3

Human HEK293 Cells
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-00978 Progranulin Protein, Human, Recombinant (His)

PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...

Human HEK293 Cells
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-05208 PD-L1 Protein, Human, Recombinant

CD274 molecule,PDCD1L1,PD-L1,PDL<...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin 1 receptor antagoni...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01862 IL-4 Protein, Human, Recombinant

Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF

Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His)

leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C

Human HEK293 Cells
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-04333 LRRC15 Protein, Human, Recombinant (hFc)

leucine rich repeat containing 15,LIB

Human HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-03531 PSGL-1/CD162 Protein, Human, Recombinant (His)

selectin P ligand,PSGL-1,PSGL1,CD1

Human HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G1<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
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重组蛋白

PARP Protein, Human, Recombinant (His)
Cat.No: TMPY-01188
Species: Human
Expression System: Baculovirus Insect Cells
PARP Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02465
Species: Mouse
Expression System: Baculovirus Insect Cells
PARP3 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02421
Species: Human
Expression System: Baculovirus Insect Cells
Caspase-7 Protein, Human, Recombinant (His)
Cat.No: TMPY-02831
Species: Human
Expression System: E. coli
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03745
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00383
Species: Human
Expression System: HEK293 Cells
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01147
Species: Human
Expression System: HEK293 Cells
CEACAM3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01850
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Human, Recombinant (His)
Cat.No: TMPY-01938
Species: Human
Expression System: HEK293 Cells
SIGIRR Protein, Human, Recombinant (His)
Cat.No: TMPY-01894
Species: Human
Expression System: HEK293 Cells
ACVR2B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01281
Species: Mouse
Expression System: HEK293 Cells
IL-13RA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01258
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
Cat.No: TMPY-01827
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Human, Recombinant
Cat.No: TMPY-00861
Species: Human
Expression System: E. coli
FLT3 Protein, Human, Recombinant (T227M, His)
Cat.No: TMPY-01247
Species: Human
Expression System: HEK293 Cells
DR5/TRAIL R2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01185
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
Cat.No: TMPY-05220
Species: Human
Expression System: HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06418
Species: Human
Expression System: HEK293 Cells
ErbB4 Protein, Human, Rhesus, Recombinant (His)
Cat.No: TMPY-02813
Species: Human,Rhesus
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
EPOR Protein, Human, Recombinant (His)
Cat.No: TMPY-01883
Species: Human
Expression System: HEK293 Cells
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
Cat.No: TMPY-04939
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04348
Species: Human
Expression System: HEK293 Cells
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04165
Species: Human
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
Cat.No: TMPY-01137
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
CD44 Protein, Human, Recombinant (His)
Cat.No: TMPY-02033
Species: Human
Expression System: HEK293 Cells
ACVR2A Protein, Human, Recombinant (His)
Cat.No: TMPY-01744
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03967
Species: Human
Expression System: HEK293 Cells
CD73 Protein, Human, Recombinant (His)
Cat.No: TMPY-01851
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (His)
Cat.No: TMPY-01949
Species: Human
Expression System: HEK293 Cells
Progranulin Protein, Human, Recombinant (His)
Cat.No: TMPY-00978
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant
Cat.No: TMPY-05208
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
IL-4 Protein, Human, Recombinant
Cat.No: TMPY-01862
Species: Human
Expression System: E. coli
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
LILRB5/CD85c Protein, Human, Recombinant (His)
Cat.No: TMPY-04826
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04333
Species: Human
Expression System: HEK293 Cells
PSGL-1/CD162 Protein, Human, Recombinant (His)
Cat.No: TMPY-03531
Species: Human
Expression System: HEK293 Cells
LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
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